BDBM50319044 (2S,3R,4R,5S,6R)-2-(4-chloro-3-((6-(pentyloxy)pyridazin-3-yl)methyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol::CHEMBL1085547::US8541380, 54

SMILES: CCCCCOc1ccc(Cc2cc(ccc2Cl)[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)nn1

InChI Key: InChIKey=WRKPEMFYICYEBT-VOFPXKNKSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50319044   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50319044 ((2S,3R,4R,5S,6R)-2-(4-chloro-3-((6-(pentyloxy)pyri...) Show SMILES CCCCCOc1ccc(Cc2cc(ccc2Cl)[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)nn1 |r| Show InChI InChI=1S/C22H29ClN2O6/c1-2-3-4-9-30-18-8-6-15(24-25-18)11-14-10-13(5-7-16(14)23)22-21(29)20(28)19(27)17(12-26)31-22/h5-8,10,17,19-22,26-29H,2-4,9,11-12H2,1H3/t17-,19-,20+,21-,22+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Green Cross Corporation Curated by ChEMBL					Assay Description Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation counting				Bioorg Med Chem Lett 20: 3420-5 (2010) Article DOI: 10.1016/j.bmcl.2010.04.006 BindingDB Entry DOI: 10.7270/Q24J0F8B
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50319044 ((2S,3R,4R,5S,6R)-2-(4-chloro-3-((6-(pentyloxy)pyri...) Show SMILES CCCCCOc1ccc(Cc2cc(ccc2Cl)[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)nn1 |r| Show InChI InChI=1S/C22H29ClN2O6/c1-2-3-4-9-30-18-8-6-15(24-25-18)11-14-10-13(5-7-16(14)23)22-21(29)20(28)19(27)17(12-26)31-22/h5-8,10,17,19-22,26-29H,2-4,9,11-12H2,1H3/t17-,19-,20+,21-,22+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Green Cross Corporation US Patent					Assay Description Inhibition assay using hSGLT2.				US Patent US8541380 (2013) BindingDB Entry DOI: 10.7270/Q2T43RQ3
					More data for this Ligand-Target Pair