BDBM50319153 8-Methoxy-3-methyl-1-propyl-4-trifluoromethyl-imidazo[1,5-a]pyrido[3,2-e]pyrazine::CHEMBL1084334

SMILES: CCCc1nc(C)c2c(nc3ccc(OC)nc3n12)C(F)(F)F

InChI Key: InChIKey=HBJUWVYAVXSGFZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50319153   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM50319153 (8-Methoxy-3-methyl-1-propyl-4-trifluoromethyl-imid...) Show SMILES CCCc1nc(C)c2c(nc3ccc(OC)nc3n12)C(F)(F)F Show InChI InChI=1S/C15H15F3N4O/c1-4-5-10-19-8(2)12-13(15(16,17)18)20-9-6-7-11(23-3)21-14(9)22(10)12/h6-7H,4-5H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
Biotie Therapies GmbH Curated by ChEMBL					Assay Description Inhibition of human recombinant PDE10A expressed in baculovirus-SF21 cell system assessed as hydrolysis of [3H]cAMP after 1 hr by liquid scintillatio...				J Med Chem 53: 4399-411 (2010) Article DOI: 10.1021/jm1002793 BindingDB Entry DOI: 10.7270/Q2MK6D3N
					More data for this Ligand-Target Pair