BDBM50319216 6-[3-(Naphthalene-2-carbonyl)-ureido]-hexanoic acid hydroxyamide::CHEMBL1085052

SMILES: ONC(=O)CCCCCNC(=O)NC(=O)c1ccc2ccccc2c1

InChI Key: InChIKey=HPXNIWNVCNUTRT-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50319216   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50319216 (6-[3-(Naphthalene-2-carbonyl)-ureido]-hexanoic aci...) Show SMILES ONC(=O)CCCCCNC(=O)NC(=O)c1ccc2ccccc2c1 Show InChI InChI=1S/C18H21N3O4/c22-16(21-25)8-2-1-5-11-19-18(24)20-17(23)15-10-9-13-6-3-4-7-14(13)12-15/h3-4,6-7,9-10,12,25H,1-2,5,8,11H2,(H,21,22)(H2,19,20,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
S *BIO Pte Ltd Curated by ChEMBL					Assay Description Inhibition of HDAC1 in human COLO205 cells assessed as induction of histone H3 acetylation				Bioorg Med Chem Lett 20: 3314-21 (2010) Article DOI: 10.1016/j.bmcl.2010.04.041 BindingDB Entry DOI: 10.7270/Q2GT5NCX
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50319216 (6-[3-(Naphthalene-2-carbonyl)-ureido]-hexanoic aci...) Show SMILES ONC(=O)CCCCCNC(=O)NC(=O)c1ccc2ccccc2c1 Show InChI InChI=1S/C18H21N3O4/c22-16(21-25)8-2-1-5-11-19-18(24)20-17(23)15-10-9-13-6-3-4-7-14(13)12-15/h3-4,6-7,9-10,12,25H,1-2,5,8,11H2,(H,21,22)(H2,19,20,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.15E+3	n/a	n/a	n/a	n/a	n/a	n/a
S *BIO Pte Ltd Curated by ChEMBL					Assay Description Inhibition of HDAC1 in human COLO205 cells assessed as induction of histone H3 acetylation				Bioorg Med Chem Lett 20: 3314-21 (2010) Article DOI: 10.1016/j.bmcl.2010.04.041 BindingDB Entry DOI: 10.7270/Q2GT5NCX
					More data for this Ligand-Target Pair