BDBM50319314 1-(4-methoxyphenyl)-2-(1-phenyl-1H-tetrazol-5-ylthio)ethanone::CHEMBL1083267

SMILES: COc1ccc(cc1)C(=O)CSc1cnnn1-c1ccccc1

InChI Key: InChIKey=DQGPVWAKCLZBNR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50319314   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50319314 (1-(4-methoxyphenyl)-2-(1-phenyl-1H-tetrazol-5-ylth...) Show SMILES COc1ccc(cc1)C(=O)CSc1cnnn1-c1ccccc1 Show InChI InChI=1S/C17H15N3O2S/c1-22-15-9-7-13(8-10-15)16(21)12-23-17-11-18-19-20(17)14-5-3-2-4-6-14/h2-11H,12H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.05E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Edinburgh Curated by ChEMBL					Assay Description Inhibition of human 11beta-HSD1 expressed in HEK293 cells by scintillation proximity assay				Bioorg Med Chem Lett 20: 3265-71 (2010) Article DOI: 10.1016/j.bmcl.2010.04.055 BindingDB Entry DOI: 10.7270/Q2ZS2WPQ
					More data for this Ligand-Target Pair