BDBM50320073 1-Benzyl-2-pentyl-1H-imidazo[4,5-c]quinolin-4-amine::CHEMBL1086474

SMILES: CCCCCc1nc2c(N)nc3ccccc3c2n1Cc1ccccc1

InChI Key: InChIKey=FKPYLOWKLOKNKU-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50320073   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Toll-like receptor 7 (Homo sapiens (Human))	BDBM50320073 (1-Benzyl-2-pentyl-1H-imidazo[4,5-c]quinolin-4-amin...) Show SMILES CCCCCc1nc2c(N)nc3ccccc3c2n1Cc1ccccc1 Show InChI InChI=1S/C22H24N4/c1-2-3-5-14-19-25-20-21(26(19)15-16-10-6-4-7-11-16)17-12-8-9-13-18(17)24-22(20)23/h4,6-13H,2-3,5,14-15H2,1H3,(H2,23,24)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	91.5	n/a	n/a	n/a	n/a
University of Kansas Curated by ChEMBL					Assay Description Agonist activity at human TLR7 expressed in NFkappaB-stimulated HEK293 cells assessed as induction of secreted alkaline phosphatase expression by rep...				J Med Chem 53: 4450-65 (2010) Article DOI: 10.1021/jm100358c BindingDB Entry DOI: 10.7270/Q2Q52PS6
					More data for this Ligand-Target Pair