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SMILES: COc1ccc(cc1)S(=O)(=O)N(Cc1ccc(-c2nnn[nH]2)c(F)c1)Cc1ccccn1

InChI Key: InChIKey=CBJBNXDBGFACAG-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50320164   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
C-X-C chemokine receptor type 3


(Homo sapiens (Human))		BDBM50320164
PNG
(CHEMBL1085508 | N-(3-fluoro-4-(1H-tetrazol-5-yl)be...)
Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1ccc(-c2nnn[nH]2)c(F)c1)Cc1ccccn1
Show InChI InChI=1S/C21H19FN6O3S/c1-31-17-6-8-18(9-7-17)32(29,30)28(14-16-4-2-3-11-23-16)13-15-5-10-19(20(22)12-15)21-24-26-27-25-21/h2-12H,13-14H2,1H3,(H,24,25,26,27)
UniProtKB/SwissProt

antibodypedia
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CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 158n/an/an/an/an/an/a



Merck Serono SA

Curated by ChEMBL


Assay Description
Antagonist activity at human CXCR3 expressed in mouse L1.2 cells assessed as inhibition of IP10-induced chemotaxis after 4 hrs

Bioorg Med Chem Lett 20: 3614-7 (2010)


Article DOI: 10.1016/j.bmcl.2010.04.113
BindingDB Entry DOI: 10.7270/Q2668DDX
More data for this
Ligand-Target Pair