BDBM50320521 4-(1,3,4-Thiadiozol-2-ylthio)pyridine-3-sulfonamide::CHEMBL1165005

SMILES: NS(=O)(=O)c1cnccc1Sc1nnns1

InChI Key: InChIKey=NBXXFQIMPOWTSV-UHFFFAOYSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50320521   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 12 (Homo sapiens (Human))	BDBM50320521 (4-(1,3,4-Thiadiozol-2-ylthio)pyridine-3-sulfonamid...) Show SMILES NS(=O)(=O)c1cnccc1Sc1nnns1 Show InChI InChI=1S/C6H5N5O2S3/c7-16(12,13)5-3-8-2-1-4(5)14-6-9-10-11-15-6/h1-3H,(H2,7,12,13)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	5.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Gdansk Curated by ChEMBL					Assay Description Inhibition of human cloned carbonic anhydrase 12 catalytic domain preincubated for 15 mins by stopped flow CO2 hydration assay				Eur J Med Chem 45: 2396-404 (2010) Article DOI: 10.1016/j.ejmech.2010.02.020 BindingDB Entry DOI: 10.7270/Q2M908W8
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Homo sapiens (Human))	BDBM50320521 (4-(1,3,4-Thiadiozol-2-ylthio)pyridine-3-sulfonamid...) Show SMILES NS(=O)(=O)c1cnccc1Sc1nnns1 Show InChI InChI=1S/C6H5N5O2S3/c7-16(12,13)5-3-8-2-1-4(5)14-6-9-10-11-15-6/h1-3H,(H2,7,12,13)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	7.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Gdansk Curated by ChEMBL					Assay Description Inhibition of human cloned carbonic anhydrase 9 catalytic domain preincubated for 15 mins by stopped flow CO2 hydration assay				Eur J Med Chem 45: 2396-404 (2010) Article DOI: 10.1016/j.ejmech.2010.02.020 BindingDB Entry DOI: 10.7270/Q2M908W8
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50320521 (4-(1,3,4-Thiadiozol-2-ylthio)pyridine-3-sulfonamid...) Show SMILES NS(=O)(=O)c1cnccc1Sc1nnns1 Show InChI InChI=1S/C6H5N5O2S3/c7-16(12,13)5-3-8-2-1-4(5)14-6-9-10-11-15-6/h1-3H,(H2,7,12,13)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	56.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Gdansk Curated by ChEMBL					Assay Description Inhibition of human cloned carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration assay				Eur J Med Chem 45: 2396-404 (2010) Article DOI: 10.1016/j.ejmech.2010.02.020 BindingDB Entry DOI: 10.7270/Q2M908W8
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM50320521 (4-(1,3,4-Thiadiozol-2-ylthio)pyridine-3-sulfonamid...) Show SMILES NS(=O)(=O)c1cnccc1Sc1nnns1 Show InChI InChI=1S/C6H5N5O2S3/c7-16(12,13)5-3-8-2-1-4(5)14-6-9-10-11-15-6/h1-3H,(H2,7,12,13)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	6.67E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Gdansk Curated by ChEMBL					Assay Description Inhibition of human cloned carbonic anhydrase 1 preincubated for 15 mins by stopped flow CO2 hydration assay				Eur J Med Chem 45: 2396-404 (2010) Article DOI: 10.1016/j.ejmech.2010.02.020 BindingDB Entry DOI: 10.7270/Q2M908W8
					More data for this Ligand-Target Pair