BDBM50320551 3-(4-Trifluoromethoxybenzylidene)anabaseine::CHEMBL1163380

SMILES: FC(F)(F)Oc1ccc(\C=C2/CCCN=C2c2cccnc2)cc1

InChI Key: InChIKey=KENIMVNHLINACQ-SDNWHVSQSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50320551   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuronal acetylcholine receptor protein alpha-4/beta-2 subunit (Rattus norvegicus (Rat))	BDBM50320551 (3-(4-Trifluoromethoxybenzylidene)anabaseine | CHEM...) Show SMILES FC(F)(F)Oc1ccc(\C=C2/CCCN=C2c2cccnc2)cc1 |c:14| Show InChI InChI=1S/C18H15F3N2O/c19-18(20,21)24-16-7-5-13(6-8-16)11-14-3-2-10-23-17(14)15-4-1-9-22-12-15/h1,4-9,11-12H,2-3,10H2/b14-11+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	929	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Florida Curated by ChEMBL					Assay Description Displacement of [3H]cytisine from alpha4beta2 nAChR in rat brain membrane after 3 hrs				Eur J Med Chem 45: 2433-46 (2010) Article DOI: 10.1016/j.ejmech.2010.02.027 BindingDB Entry DOI: 10.7270/Q27081M9
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor protein alpha-4/beta-2 subunit (Rattus norvegicus (Rat))	BDBM50320551 (3-(4-Trifluoromethoxybenzylidene)anabaseine | CHEM...) Show SMILES FC(F)(F)Oc1ccc(\C=C2/CCCN=C2c2cccnc2)cc1 |c:14| Show InChI InChI=1S/C18H15F3N2O/c19-18(20,21)24-16-7-5-13(6-8-16)11-14-3-2-10-23-17(14)15-4-1-9-22-12-15/h1,4-9,11-12H,2-3,10H2/b14-11+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	929	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Florida Curated by ChEMBL					Assay Description Displacement of [3H]cytisine from alpha4beta2 nAChR in rat brain membrane after 3 hrs				Eur J Med Chem 45: 2433-46 (2010) Article DOI: 10.1016/j.ejmech.2010.02.027 BindingDB Entry DOI: 10.7270/Q27081M9
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor (Rattus norvegicus (Rat))	BDBM50320551 (3-(4-Trifluoromethoxybenzylidene)anabaseine | CHEM...) Show SMILES FC(F)(F)Oc1ccc(\C=C2/CCCN=C2c2cccnc2)cc1 |c:14| Show InChI InChI=1S/C18H15F3N2O/c19-18(20,21)24-16-7-5-13(6-8-16)11-14-3-2-10-23-17(14)15-4-1-9-22-12-15/h1,4-9,11-12H,2-3,10H2/b14-11+	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	929	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Florida Curated by ChEMBL					Assay Description Displacement of [125I]-alpha-bungarotoxin from alpha7 nAChR in rat brain membrane after 3 hrs				Eur J Med Chem 45: 2433-46 (2010) Article DOI: 10.1016/j.ejmech.2010.02.027 BindingDB Entry DOI: 10.7270/Q27081M9
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor (Rattus norvegicus (Rat))	BDBM50320551 (3-(4-Trifluoromethoxybenzylidene)anabaseine | CHEM...) Show SMILES FC(F)(F)Oc1ccc(\C=C2/CCCN=C2c2cccnc2)cc1 |c:14| Show InChI InChI=1S/C18H15F3N2O/c19-18(20,21)24-16-7-5-13(6-8-16)11-14-3-2-10-23-17(14)15-4-1-9-22-12-15/h1,4-9,11-12H,2-3,10H2/b14-11+	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	929	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Florida Curated by ChEMBL					Assay Description Displacement of [125I]-alpha-bungarotoxin from alpha7 nAChR in rat brain membrane after 3 hrs				Eur J Med Chem 45: 2433-46 (2010) Article DOI: 10.1016/j.ejmech.2010.02.027 BindingDB Entry DOI: 10.7270/Q27081M9
					More data for this Ligand-Target Pair