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SMILES: CCCc1nc(c(CNCCN2CCN(CC2)c2ccc(C)cc2C)o1)-c1ccccc1

InChI Key: InChIKey=UWKLNFSFIWJPQS-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50321399   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Voltage-dependent T-type calcium channel subunit alpha-1G


(Homo sapiens (Human))		BDBM50321399
PNG
(2-(4-(2,4-dimethylphenyl)piperazin-1-yl)-N-((4-phe...)
Show SMILES CCCc1nc(c(CNCCN2CCN(CC2)c2ccc(C)cc2C)o1)-c1ccccc1
Show InChI InChI=1S/C27H36N4O/c1-4-8-26-29-27(23-9-6-5-7-10-23)25(32-26)20-28-13-14-30-15-17-31(18-16-30)24-12-11-21(2)19-22(24)3/h5-7,9-12,19,28H,4,8,13-18,20H2,1-3H3
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Article
PubMed
n/an/a 2.22E+3n/an/an/an/an/an/a



Institute of Science and Technology

Curated by ChEMBL


Assay Description
Inhibition of T-type CaV3.1 channel expressed in HEK293 cells assessed as inhibition of calcium current by automated patch-clamp assay

Bioorg Med Chem Lett 20: 4219-22 (2010)


Article DOI: 10.1016/j.bmcl.2010.05.030
BindingDB Entry DOI: 10.7270/Q2PN96KW
More data for this
Ligand-Target Pair