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SMILES: CCCc1nc(c(CNCCCN2CCN(CC2)c2ccc(F)cc2)o1)-c1ccccc1

InChI Key: InChIKey=QTXOMIHNMOCASO-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50321403   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Voltage-dependent T-type calcium channel subunit alpha-1G


(Homo sapiens (Human))		BDBM50321403
PNG
(3-(4-(4-fluorophenyl)piperazin-1-yl)-N-((4-phenyl-...)
Show SMILES CCCc1nc(c(CNCCCN2CCN(CC2)c2ccc(F)cc2)o1)-c1ccccc1
Show InChI InChI=1S/C26H33FN4O/c1-2-7-25-29-26(21-8-4-3-5-9-21)24(32-25)20-28-14-6-15-30-16-18-31(19-17-30)23-12-10-22(27)11-13-23/h3-5,8-13,28H,2,6-7,14-20H2,1H3
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Article
PubMed
n/an/a 3.21E+3n/an/an/an/an/an/a



Institute of Science and Technology

Curated by ChEMBL


Assay Description
Inhibition of T-type CaV3.1 channel expressed in HEK293 cells assessed as inhibition of calcium current by automated patch-clamp assay

Bioorg Med Chem Lett 20: 4219-22 (2010)


Article DOI: 10.1016/j.bmcl.2010.05.030
BindingDB Entry DOI: 10.7270/Q2PN96KW
More data for this
Ligand-Target Pair