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SMILES: CCCc1nc(c(CNCCCN2CCN(CC2)c2cccc(c2)C(F)(F)F)o1)-c1ccccc1

InChI Key: InChIKey=URXQLFJLHJOMLX-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50321410   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Voltage-dependent T-type calcium channel subunit alpha-1G


(Homo sapiens (Human))		BDBM50321410
PNG
(CHEMBL1170780 | N-((4-phenyl-2-propyloxazol-5-yl)m...)
Show SMILES CCCc1nc(c(CNCCCN2CCN(CC2)c2cccc(c2)C(F)(F)F)o1)-c1ccccc1
Show InChI InChI=1S/C27H33F3N4O/c1-2-8-25-32-26(21-9-4-3-5-10-21)24(35-25)20-31-13-7-14-33-15-17-34(18-16-33)23-12-6-11-22(19-23)27(28,29)30/h3-6,9-12,19,31H,2,7-8,13-18,20H2,1H3
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Institute of Science and Technology

Curated by ChEMBL


Assay Description
Inhibition of T-type CaV3.1 channel expressed in HEK293 cells assessed as inhibition of calcium current by automated patch-clamp assay

Bioorg Med Chem Lett 20: 4219-22 (2010)


Article DOI: 10.1016/j.bmcl.2010.05.030
BindingDB Entry DOI: 10.7270/Q2PN96KW
More data for this
Ligand-Target Pair