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BDBM50321428 1-(4-(4-(6-amino-5-(benzo[d]oxazol-2-yl)pyridin-3-yl)-1H-pyrazol-1-yl)piperidin-1-yl)propan-1-one tetrahydrochloride::CHEMBL1170926

SMILES: CCC(=O)N1CCC(CC1)n1cc(cn1)-c1cnc(N)c(c1)-c1nc2ccccc2o1

InChI Key: InChIKey=GEEVDRJPBXLINN-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50321428   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50321428
PNG
(1-(4-(4-(6-amino-5-(benzo[d]oxazol-2-yl)pyridin-3-...)
Show SMILES CCC(=O)N1CCC(CC1)n1cc(cn1)-c1cnc(N)c(c1)-c1nc2ccccc2o1
Show InChI InChI=1S/C23H24N6O2/c1-2-21(30)28-9-7-17(8-10-28)29-14-16(13-26-29)15-11-18(22(24)25-12-15)23-27-19-5-3-4-6-20(19)31-23/h3-6,11-14,17H,2,7-10H2,1H3,(H2,24,25)
PDB
MMDB

KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

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DrugBank
antibodypedia
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CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 7n/an/an/an/an/an/a



Korea Research Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant c-MET by HTRF assay


Bioorg Med Chem Lett 20: 4223-7 (2010)


Article DOI: 10.1016/j.bmcl.2010.05.031
BindingDB Entry DOI: 10.7270/Q2JW8FTQ
More data for this
Ligand-Target Pair