BDBM50321433 CHEMBL1169794::methyl 4-(4-(6-amino-5-(benzo[d]oxazol-2-yl)pyridin-3-yl)-1H-pyrazol-1-yl)piperidine-1-carboxylate tetrahydrochloride

SMILES: COC(=O)N1CCC(CC1)n1cc(cn1)-c1cnc(N)c(c1)-c1nc2ccccc2o1

InChI Key: InChIKey=BTERWJGRHAZWQN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50321433   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50321433 (CHEMBL1169794 | methyl 4-(4-(6-amino-5-(benzo[d]ox...) Show SMILES COC(=O)N1CCC(CC1)n1cc(cn1)-c1cnc(N)c(c1)-c1nc2ccccc2o1 Show InChI InChI=1S/C22H22N6O3/c1-30-22(29)27-8-6-16(7-9-27)28-13-15(12-25-28)14-10-17(20(23)24-11-14)21-26-18-4-2-3-5-19(18)31-21/h2-5,10-13,16H,6-9H2,1H3,(H2,23,24)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of recombinant c-MET by HTRF assay				Bioorg Med Chem Lett 20: 4223-7 (2010) Article DOI: 10.1016/j.bmcl.2010.05.031 BindingDB Entry DOI: 10.7270/Q2JW8FTQ
					More data for this Ligand-Target Pair