BDBM50321780 (R)-6'-methoxy-1'-phenyl-1-propyl-6',7'-dihydro-1'H-spiro[piperidine-4,4'-pyrano[4,3-c]pyrazole]::CHEMBL1172059

SMILES: CCCN1CCC2(CC1)O[C@H](Cc1c2cnn1-c1ccccc1)OC

InChI Key: InChIKey=CQOWRZAMLIMIMA-LJQANCHMSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50321780   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50321780 ((R)-6'-methoxy-1'-phenyl-1-propyl-6',7'-dihydro-1'...) Show SMILES CCCN1CCC2(CC1)O[C@H](Cc1c2cnn1-c1ccccc1)OC |r| Show InChI InChI=1S/C20H27N3O2/c1-3-11-22-12-9-20(10-13-22)17-15-21-23(16-7-5-4-6-8-16)18(17)14-19(24-2)25-20/h4-8,15,19H,3,9-14H2,1-2H3/t19-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	33	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institut f£r Pharmazeutische und Medizinische Chemie der Universit£t M£nster Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in guinea pig brain membrane				Eur J Med Chem 45: 3116-24 (2010) Article DOI: 10.1016/j.ejmech.2010.03.048 BindingDB Entry DOI: 10.7270/Q2XD11V4
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50321780 ((R)-6'-methoxy-1'-phenyl-1-propyl-6',7'-dihydro-1'...) Show SMILES CCCN1CCC2(CC1)O[C@H](Cc1c2cnn1-c1ccccc1)OC |r| Show InChI InChI=1S/C20H27N3O2/c1-3-11-22-12-9-20(10-13-22)17-15-21-23(16-7-5-4-6-8-16)18(17)14-19(24-2)25-20/h4-8,15,19H,3,9-14H2,1-2H3/t19-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	33	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institut f£r Pharmazeutische und Medizinische Chemie der Universit£t M£nster Curated by ChEMBL					Assay Description Displacement of (+)-[3H]pentazocine from guinea pig brain sigma 1 receptor after 180 mins by scintillation counting				J Med Chem 54: 6704-13 (2011) Article DOI: 10.1021/jm200585k BindingDB Entry DOI: 10.7270/Q22R3SN0
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50321780 ((R)-6'-methoxy-1'-phenyl-1-propyl-6',7'-dihydro-1'...) Show SMILES CCCN1CCC2(CC1)O[C@H](Cc1c2cnn1-c1ccccc1)OC |r| Show InChI InChI=1S/C20H27N3O2/c1-3-11-22-12-9-20(10-13-22)17-15-21-23(16-7-5-4-6-8-16)18(17)14-19(24-2)25-20/h4-8,15,19H,3,9-14H2,1-2H3/t19-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	210	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institut f£r Pharmazeutische und Medizinische Chemie der Universit£t M£nster Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in guinea pig brain membrane				Eur J Med Chem 45: 3116-24 (2010) Article DOI: 10.1016/j.ejmech.2010.03.048 BindingDB Entry DOI: 10.7270/Q2XD11V4
					More data for this Ligand-Target Pair