BDBM50321830 CHEMBL1173157::N1-{5-[4-(trifluoromethyl)phenyl]oxazol-2-yl}-5,6,7,8-tetrahydronaphthalene-1,7-diamine

SMILES: NC1CCc2cccc(Nc3ncc(o3)-c3ccc(cc3)C(F)(F)F)c2C1

InChI Key: InChIKey=CAZPUPYLGDBILQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50321830   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50321830 (CHEMBL1173157 | N1-{5-[4-(trifluoromethyl)phenyl]o...) Show SMILES NC1CCc2cccc(Nc3ncc(o3)-c3ccc(cc3)C(F)(F)F)c2C1 Show InChI InChI=1S/C20H18F3N3O/c21-20(22,23)14-7-4-13(5-8-14)18-11-25-19(27-18)26-17-3-1-2-12-6-9-15(24)10-16(12)17/h1-5,7-8,11,15H,6,9-10,24H2,(H,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	327	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Antagonist activity at human recombinant TRPV1 receptor expressed in human 1321 cells assessed as inhibition of capsaicin-induced in intracellular ca...				Bioorg Med Chem 18: 4821-9 (2011) Article DOI: 10.1016/j.bmc.2010.04.099 BindingDB Entry DOI: 10.7270/Q27H1KJJ
					More data for this Ligand-Target Pair