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BDBM50321849 8-(4-Phenyloxazol-2-ylamino)-1,2,3,4-tetrahydronaphthalen-2-ol::CHEMBL1172952

SMILES: OC1CCc2cccc(Nc3nc(co3)-c3ccccc3)c2C1

InChI Key: InChIKey=RBWFGIICTLJYDD-UHFFFAOYSA-N

Data: 1 IC50

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50321849   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))
BDBM50321849
PNG
(8-(4-Phenyloxazol-2-ylamino)-1,2,3,4-tetrahydronap...)
Show SMILES OC1CCc2cccc(Nc3nc(co3)-c3ccccc3)c2C1
Show InChI InChI=1S/C19H18N2O2/c22-15-10-9-13-7-4-8-17(16(13)11-15)20-19-21-18(12-23-19)14-5-2-1-3-6-14/h1-8,12,15,22H,9-11H2,(H,20,21)
PDB
MMDB

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PC cid
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Article
PubMed
n/an/a 864n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Antagonist activity at human recombinant TRPV1 receptor expressed in human 1321 cells assessed as inhibition of capsaicin-induced in intracellular ca...


Bioorg Med Chem 18: 4821-9 (2011)


Article DOI: 10.1016/j.bmc.2010.04.099
BindingDB Entry DOI: 10.7270/Q27H1KJJ
More data for this
Ligand-Target Pair