BDBM50322094 3-(phenylsulfonyl)-N-(pyridin-3-ylmethyl)thieno[2,3-e][1,2,3]triazolo[1,5-a]pyrimidin-5-amine::CHEMBL1173135

SMILES: O=S(=O)(c1nnn2c3ccsc3c(NCc3cccnc3)nc12)c1ccccc1

InChI Key: InChIKey=JOSRKQJPJLVRAI-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50322094   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50322094 (3-(phenylsulfonyl)-N-(pyridin-3-ylmethyl)thieno[2,...) Show SMILES O=S(=O)(c1nnn2c3ccsc3c(NCc3cccnc3)nc12)c1ccccc1 Show InChI InChI=1S/C19H14N6O2S2/c26-29(27,14-6-2-1-3-7-14)19-18-22-17(21-12-13-5-4-9-20-11-13)16-15(8-10-28-16)25(18)24-23-19/h1-11H,12H2,(H,21,22)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
Chemical Diversity Research Institute Curated by ChEMBL					Assay Description Antagonist activity at human recombinant 5HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced cAMP production				Bioorg Med Chem 18: 5282-90 (2010) Article DOI: 10.1016/j.bmc.2010.05.051 BindingDB Entry DOI: 10.7270/Q2F190QT
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50322094 (3-(phenylsulfonyl)-N-(pyridin-3-ylmethyl)thieno[2,...) Show SMILES O=S(=O)(c1nnn2c3ccsc3c(NCc3cccnc3)nc12)c1ccccc1 Show InChI InChI=1S/C19H14N6O2S2/c26-29(27,14-6-2-1-3-7-14)19-18-22-17(21-12-13-5-4-9-20-11-13)16-15(8-10-28-16)25(18)24-23-19/h1-11H,12H2,(H,21,22)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>30	n/a	n/a	n/a	n/a	n/a	n/a
Chemical Diversity Research Institute Curated by ChEMBL					Assay Description Binding affinity to human recombinant 5HT6 receptor expressed in HEK293 cells by radioligand displacement assay				Bioorg Med Chem 18: 5282-90 (2010) Article DOI: 10.1016/j.bmc.2010.05.051 BindingDB Entry DOI: 10.7270/Q2F190QT
					More data for this Ligand-Target Pair