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SMILES: CC(C)CCNc1nc2c(nnn2c2ccsc12)S(=O)(=O)c1cccc(Cl)c1

InChI Key: InChIKey=PIQRWEDERISCSU-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50322192   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
5-hydroxytryptamine receptor 6


(Homo sapiens (Human))		BDBM50322192
PNG
(3-(3-chlorophenylsulfonyl)-N-isopentylthieno[2,3-e...)
Show SMILES CC(C)CCNc1nc2c(nnn2c2ccsc12)S(=O)(=O)c1cccc(Cl)c1
Show InChI InChI=1S/C18H18ClN5O2S2/c1-11(2)6-8-20-16-15-14(7-9-27-15)24-17(21-16)18(22-23-24)28(25,26)13-5-3-4-12(19)10-13/h3-5,7,9-11H,6,8H2,1-2H3,(H,20,21)
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n/an/a 68n/an/an/an/an/an/a



Chemical Diversity Research Institute

Curated by ChEMBL


Assay Description
Antagonist activity at human recombinant 5HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced cAMP production

Bioorg Med Chem 18: 5282-90 (2010)


Article DOI: 10.1016/j.bmc.2010.05.051
BindingDB Entry DOI: 10.7270/Q2F190QT
More data for this
Ligand-Target Pair