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SMILES: COCCNc1nc2c(nnn2c2ccsc12)S(=O)(=O)c1cccc(Cl)c1

InChI Key: InChIKey=YEJMWCSTHKLOQC-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50322193   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
5-hydroxytryptamine receptor 6


(Homo sapiens (Human))		BDBM50322193
PNG
(3-(3-chlorophenylsulfonyl)-N-(2-methoxyethyl)thien...)
Show SMILES COCCNc1nc2c(nnn2c2ccsc12)S(=O)(=O)c1cccc(Cl)c1
Show InChI InChI=1S/C16H14ClN5O3S2/c1-25-7-6-18-14-13-12(5-8-26-13)22-15(19-14)16(20-21-22)27(23,24)11-4-2-3-10(17)9-11/h2-5,8-9H,6-7H2,1H3,(H,18,19)
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n/an/a 110n/an/an/an/an/an/a



Chemical Diversity Research Institute

Curated by ChEMBL


Assay Description
Antagonist activity at human recombinant 5HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced cAMP production

Bioorg Med Chem 18: 5282-90 (2010)


Article DOI: 10.1016/j.bmc.2010.05.051
BindingDB Entry DOI: 10.7270/Q2F190QT
More data for this
Ligand-Target Pair