BDBM50322382 (R)-N-ethyl-1-(5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrrolidin-3-amine::CHEMBL1173305

SMILES: CCN[C@@H]1CCN(C1)c1ncnc2[nH]cc(C)c12

InChI Key: InChIKey=IAXCHEZVLGNNCH-SNVBAGLBSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50322382   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human))	BDBM50322382 ((R)-N-ethyl-1-(5-methyl-7H-pyrrolo[2,3-d]pyrimidin...) Show SMILES CCN[C@@H]1CCN(C1)c1ncnc2[nH]cc(C)c12 |r| Show InChI InChI=1S/C13H19N5/c1-3-14-10-4-5-18(7-10)13-11-9(2)6-15-12(11)16-8-17-13/h6,8,10,14H,3-5,7H2,1-2H3,(H,15,16,17)/t10-/m1/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of AKT1 after 90 mins by IMAP assay				J Med Chem 53: 4615-22 (2010) Article DOI: 10.1021/jm1003842 BindingDB Entry DOI: 10.7270/Q24X580C
					More data for this Ligand-Target Pair