BDBM50322386 (R)-N-(1-(5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrrolidin-3-yl)benzamide::CHEMBL1170238

SMILES: Cc1c[nH]c2ncnc(N3CC[C@H](C3)NC(=O)c3ccccc3)c12

InChI Key: InChIKey=KOXOYCKSGKSAKU-CQSZACIVSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50322386   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human))	BDBM50322386 ((R)-N-(1-(5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl...) Show SMILES Cc1c[nH]c2ncnc(N3CC[C@H](C3)NC(=O)c3ccccc3)c12 |r| Show InChI InChI=1S/C18H19N5O/c1-12-9-19-16-15(12)17(21-11-20-16)23-8-7-14(10-23)22-18(24)13-5-3-2-4-6-13/h2-6,9,11,14H,7-8,10H2,1H3,(H,22,24)(H,19,20,21)/t14-/m1/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of AKT1 after 90 mins by IMAP assay				J Med Chem 53: 4615-22 (2010) Article DOI: 10.1021/jm1003842 BindingDB Entry DOI: 10.7270/Q24X580C
					More data for this Ligand-Target Pair