BDBM50322410 (3-amino-1-(5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrrolidin-3-yl)methylcarbamic chloride::CHEMBL1171299

SMILES: Cc1c[nH]c2ncnc(N3CCC(N)(CNC(Cl)=O)C3)c12

InChI Key: InChIKey=ORWBSTVTJQRZPZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50322410   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human))	BDBM50322410 ((3-amino-1-(5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-...) Show SMILES Cc1c[nH]c2ncnc(N3CCC(N)(CNC(Cl)=O)C3)c12 Show InChI InChI=1S/C13H17ClN6O/c1-8-4-16-10-9(8)11(19-7-18-10)20-3-2-13(15,6-20)5-17-12(14)21/h4,7H,2-3,5-6,15H2,1H3,(H,17,21)(H,16,18,19)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of AKT1 after 90 mins by IMAP assay				J Med Chem 53: 4615-22 (2010) Article DOI: 10.1021/jm1003842 BindingDB Entry DOI: 10.7270/Q24X580C
					More data for this Ligand-Target Pair