null

SMILES: CC(Oc1ccc(cc1C(=O)N1CCN(CC1)c1ccc(nn1)C(F)(F)F)S(C)(=O)=O)C(F)(F)F

InChI Key: InChIKey=WKKOHQLJDSOVDS-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50322450   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human))	BDBM50322450 (CHEMBL1171648 | rac-[5-Methanesulfonyl-2-(2,2,2-tr...) Show SMILES CC(Oc1ccc(cc1C(=O)N1CCN(CC1)c1ccc(nn1)C(F)(F)F)S(C)(=O)=O)C(F)(F)F Show InChI InChI=1S/C20H20F6N4O4S/c1-12(19(21,22)23)34-15-4-3-13(35(2,32)33)11-14(15)18(31)30-9-7-29(8-10-30)17-6-5-16(27-28-17)20(24,25)26/h3-6,11-12H,7-10H2,1-2H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	900	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Inhibition of human GlyT1b expressed in CHO cells assessed as inhibition of [3H]glycine uptake by liquid scintillation counting				J Med Chem 53: 4603-14 (2010) Article DOI: 10.1021/jm100210p BindingDB Entry DOI: 10.7270/Q28916TT
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 2 (Homo sapiens (Human))	BDBM50322450 (CHEMBL1171648 | rac-[5-Methanesulfonyl-2-(2,2,2-tr...) Show SMILES CC(Oc1ccc(cc1C(=O)N1CCN(CC1)c1ccc(nn1)C(F)(F)F)S(C)(=O)=O)C(F)(F)F Show InChI InChI=1S/C20H20F6N4O4S/c1-12(19(21,22)23)34-15-4-3-13(35(2,32)33)11-14(15)18(31)30-9-7-29(8-10-30)17-6-5-16(27-28-17)20(24,25)26/h3-6,11-12H,7-10H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Inhibition of human GlyT2 expressed in CHO cells assessed as inhibition of [3H]glycine uptake by liquid scintillation counting				J Med Chem 53: 4603-14 (2010) Article DOI: 10.1021/jm100210p BindingDB Entry DOI: 10.7270/Q28916TT
					More data for this Ligand-Target Pair