null

SMILES: CC[C@H](C)[C@H](NC(=O)N1CCC2(CC1)C(N(C2=O)c1cccc(F)c1)c1ccc(Cl)cc1)C(=O)OC#N

InChI Key: InChIKey=KGMXXXLUOOBEMV-QPTFRZOZSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50322948   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM50322948 ((2S,3S)-2-(1-(4-chlorophenyl)-2-(3-fluorophenyl)-3...) Show SMILES CC[C@H](C)[C@H](NC(=O)N1CCC2(CC1)C(N(C2=O)c1cccc(F)c1)c1ccc(Cl)cc1)C(=O)OC#N |r| Show InChI InChI=1S/C27H28ClFN4O4/c1-3-17(2)22(24(34)37-16-30)31-26(36)32-13-11-27(12-14-32)23(18-7-9-19(28)10-8-18)33(25(27)35)21-6-4-5-20(29)15-21/h4-10,15,17,22-23H,3,11-14H2,1-2H3,(H,31,36)/t17-,22-,23?/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Inhibition of human CaV3.2 expressed in HEK293 cells at -100 mV membrane potential by Ionworks HT assay				Bioorg Med Chem Lett 20: 4602-6 (2010) Article DOI: 10.1016/j.bmcl.2010.06.012 BindingDB Entry DOI: 10.7270/Q2NS0V34
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM50322948 ((2S,3S)-2-(1-(4-chlorophenyl)-2-(3-fluorophenyl)-3...) Show SMILES CC[C@H](C)[C@H](NC(=O)N1CCC2(CC1)C(N(C2=O)c1cccc(F)c1)c1ccc(Cl)cc1)C(=O)OC#N |r| Show InChI InChI=1S/C27H28ClFN4O4/c1-3-17(2)22(24(34)37-16-30)31-26(36)32-13-11-27(12-14-32)23(18-7-9-19(28)10-8-18)33(25(27)35)21-6-4-5-20(29)15-21/h4-10,15,17,22-23H,3,11-14H2,1-2H3,(H,31,36)/t17-,22-,23?/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Inhibition of human CaV3.2 expressed in HEK293 cells at -100 mV membrane potential by whole cell path clamp method				Bioorg Med Chem Lett 20: 4602-6 (2010) Article DOI: 10.1016/j.bmcl.2010.06.012 BindingDB Entry DOI: 10.7270/Q2NS0V34
					More data for this Ligand-Target Pair