BDBM50323262 6-(4-ethoxy-3-(trifluoromethyl)phenyl)-1-(3-morpholinopropyl)-1H-imidazo[4,5-c]pyridine-4-carbonitrile::CHEMBL1208906

SMILES: CCOc1ccc(cc1C(F)(F)F)-c1cc2n(CCCN3CCOCC3)cnc2c(n1)C#N

InChI Key: InChIKey=MCSWMEWSUXLNDE-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50323262   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cathepsin S (Homo sapiens (Human))	BDBM50323262 (6-(4-ethoxy-3-(trifluoromethyl)phenyl)-1-(3-morpho...) Show SMILES CCOc1ccc(cc1C(F)(F)F)-c1cc2n(CCCN3CCOCC3)cnc2c(n1)C#N Show InChI InChI=1S/C23H24F3N5O2/c1-2-33-21-5-4-16(12-17(21)23(24,25)26)18-13-20-22(19(14-27)29-18)28-15-31(20)7-3-6-30-8-10-32-11-9-30/h4-5,12-13,15H,2-3,6-11H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human cathepsin S by fluorescence assay				Bioorg Med Chem Lett 20: 4350-4 (2010) Article DOI: 10.1016/j.bmcl.2010.06.072 BindingDB Entry DOI: 10.7270/Q2028RR9
					More data for this Ligand-Target Pair
Cathepsin K (Homo sapiens (Human))	BDBM50323262 (6-(4-ethoxy-3-(trifluoromethyl)phenyl)-1-(3-morpho...) Show SMILES CCOc1ccc(cc1C(F)(F)F)-c1cc2n(CCCN3CCOCC3)cnc2c(n1)C#N Show InChI InChI=1S/C23H24F3N5O2/c1-2-33-21-5-4-16(12-17(21)23(24,25)26)18-13-20-22(19(14-27)29-18)28-15-31(20)7-3-6-30-8-10-32-11-9-30/h4-5,12-13,15H,2-3,6-11H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	513	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human cathepsin K by fluorescence assay				Bioorg Med Chem Lett 20: 4350-4 (2010) Article DOI: 10.1016/j.bmcl.2010.06.072 BindingDB Entry DOI: 10.7270/Q2028RR9
					More data for this Ligand-Target Pair