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SMILES: COc1ccccc1NC(=O)c1cc(F)cc(c1)C#N

InChI Key: InChIKey=AWLPOHBSWXCQPN-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50323284   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Metabotropic glutamate receptor 5


(Rattus norvegicus (Rat))		BDBM50323284
PNG
(3-cyano-5-fluoro-N-(2-methoxyphenyl)benzamide | CH...)
Show SMILES COc1ccccc1NC(=O)c1cc(F)cc(c1)C#N
Show InChI InChI=1S/C15H11FN2O2/c1-20-14-5-3-2-4-13(14)18-15(19)11-6-10(9-17)7-12(16)8-11/h2-8H,1H3,(H,18,19)
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Article
PubMed
n/an/a>3.00E+4n/an/an/an/an/an/a



Vanderbilt University Medical Center

Curated by ChEMBL


Assay Description
Antagonist activity at rat mGlu5 receptor expressed in HEK293A cells assessed as inhibition of glutamate-induced calcium mobilization

Bioorg Med Chem Lett 20: 4390-4 (2010)


Article DOI: 10.1016/j.bmcl.2010.06.064
BindingDB Entry DOI: 10.7270/Q2V9888D
More data for this
Ligand-Target Pair