null

SMILES: Cc1cccc(NC(=O)O\N=C(\C(Cc2cccc(F)c2)C2CCCCC2)C2CCCCC2)c1

InChI Key: InChIKey=UYLJHBIHLMHLDX-VEWQFJOQSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50323364   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50323364 (1,2-dicyclohexyl-3-(3-fluorophenyl)propan-1-one O-...) Show SMILES Cc1cccc(NC(=O)O\N=C(\C(Cc2cccc(F)c2)C2CCCCC2)C2CCCCC2)c1 Show InChI InChI=1S/C29H37FN2O2/c1-21-10-8-17-26(18-21)31-29(33)34-32-28(24-14-6-3-7-15-24)27(23-12-4-2-5-13-23)20-22-11-9-16-25(30)19-22/h8-11,16-19,23-24,27H,2-7,12-15,20H2,1H3,(H,31,33)/b32-28+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	56	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]-M-MPEP from rat mGLUR5				Bioorg Med Chem Lett 20: 4371-5 (2010) Article DOI: 10.1016/j.bmcl.2010.06.075 BindingDB Entry DOI: 10.7270/Q2G1611F
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50323364 (1,2-dicyclohexyl-3-(3-fluorophenyl)propan-1-one O-...) Show SMILES Cc1cccc(NC(=O)O\N=C(\C(Cc2cccc(F)c2)C2CCCCC2)C2CCCCC2)c1 Show InChI InChI=1S/C29H37FN2O2/c1-21-10-8-17-26(18-21)31-29(33)34-32-28(24-14-6-3-7-15-24)27(23-12-4-2-5-13-23)20-22-11-9-16-25(30)19-22/h8-11,16-19,23-24,27H,2-7,12-15,20H2,1H3,(H,31,33)/b32-28+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	224	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Antagonist activity at mGLUR5 in rat E17 cells assessed as calcium accumulation by fluorimetry				Bioorg Med Chem Lett 20: 4371-5 (2010) Article DOI: 10.1016/j.bmcl.2010.06.075 BindingDB Entry DOI: 10.7270/Q2G1611F
					More data for this Ligand-Target Pair