null

SMILES: Fc1cccc(CC(C2CCCCC2)C(=N\OC(=O)Nc2cccc(Cl)c2)\C2CCCCC2)c1

InChI Key: InChIKey=IDGHBLJDJAIAAN-QVAGMWBUSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50323366   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50323366 (1,2-dicyclohexyl-3-(3-fluorophenyl)propan-1-one O-...) Show SMILES Fc1cccc(CC(C2CCCCC2)C(=N\OC(=O)Nc2cccc(Cl)c2)\C2CCCCC2)c1 Show InChI InChI=1S/C28H34ClFN2O2/c29-23-14-8-16-25(19-23)31-28(33)34-32-27(22-12-5-2-6-13-22)26(21-10-3-1-4-11-21)18-20-9-7-15-24(30)17-20/h7-9,14-17,19,21-22,26H,1-6,10-13,18H2,(H,31,33)/b32-27+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]-M-MPEP from rat mGLUR5				Bioorg Med Chem Lett 20: 4371-5 (2010) Article DOI: 10.1016/j.bmcl.2010.06.075 BindingDB Entry DOI: 10.7270/Q2G1611F
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50323366 (1,2-dicyclohexyl-3-(3-fluorophenyl)propan-1-one O-...) Show SMILES Fc1cccc(CC(C2CCCCC2)C(=N\OC(=O)Nc2cccc(Cl)c2)\C2CCCCC2)c1 Show InChI InChI=1S/C28H34ClFN2O2/c29-23-14-8-16-25(19-23)31-28(33)34-32-27(22-12-5-2-6-13-22)26(21-10-3-1-4-11-21)18-20-9-7-15-24(30)17-20/h7-9,14-17,19,21-22,26H,1-6,10-13,18H2,(H,31,33)/b32-27+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	127	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Antagonist activity at mGLUR5 in rat E17 cells assessed as calcium accumulation by fluorimetry				Bioorg Med Chem Lett 20: 4371-5 (2010) Article DOI: 10.1016/j.bmcl.2010.06.075 BindingDB Entry DOI: 10.7270/Q2G1611F
					More data for this Ligand-Target Pair