null
SMILES: O=C(Nc1ccccc1)O\N=C1/CCCCC1Cn1ccnc1
InChI Key: InChIKey=OXUWVXHBRRNACY-CAPFRKAQSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat)) | BDBM50323382![]() ((E)-2-((1H-imidazol-1-yl)methyl)cyclohexanone O-ph...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 104 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Gedeon Richter Plc Curated by ChEMBL | Assay Description Displacement of [3H]-M-MPEP from rat mGLUR5 | Bioorg Med Chem Lett 20: 4371-5 (2010) Article DOI: 10.1016/j.bmcl.2010.06.075 BindingDB Entry DOI: 10.7270/Q2G1611F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat)) | BDBM50323382![]() ((E)-2-((1H-imidazol-1-yl)methyl)cyclohexanone O-ph...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 242 | n/a | n/a | n/a | n/a | n/a | n/a |
Gedeon Richter Plc Curated by ChEMBL | Assay Description Antagonist activity at mGLUR5 in rat E17 cells assessed as calcium accumulation by fluorimetry | Bioorg Med Chem Lett 20: 4371-5 (2010) Article DOI: 10.1016/j.bmcl.2010.06.075 BindingDB Entry DOI: 10.7270/Q2G1611F | |||||||||||
More data for this Ligand-Target Pair |