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SMILES: Clc1cccc(NC(=O)O\N=C(\C(CN2CCOCC2)C2CCCCC2)C2CCCCC2)c1

InChI Key: InChIKey=KEUIDDLEADHUGQ-XLVZBRSZSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50323385   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Metabotropic glutamate receptor 5


(Rattus norvegicus (Rat))		BDBM50323385
PNG
(1,2-dicyclohexyl-3-morpholinopropan-1-one O-3-chlo...)
Show SMILES Clc1cccc(NC(=O)O\N=C(\C(CN2CCOCC2)C2CCCCC2)C2CCCCC2)c1
Show InChI InChI=1S/C26H38ClN3O3/c27-22-12-7-13-23(18-22)28-26(31)33-29-25(21-10-5-2-6-11-21)24(20-8-3-1-4-9-20)19-30-14-16-32-17-15-30/h7,12-13,18,20-21,24H,1-6,8-11,14-17,19H2,(H,28,31)/b29-25+
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PC cid
PC sid
UniChem
Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Gedeon Richter Plc

Curated by ChEMBL


Assay Description
Antagonist activity at mGLUR5 in rat E17 cells assessed as calcium accumulation by fluorimetry

Bioorg Med Chem Lett 20: 4371-5 (2010)


Article DOI: 10.1016/j.bmcl.2010.06.075
BindingDB Entry DOI: 10.7270/Q2G1611F
More data for this
Ligand-Target Pair