null

SMILES: FC(F)(F)C(=O)NCCNCCCNCCNC(=O)C(F)(F)F

InChI Key: InChIKey=OOCHSWKGVKRYIA-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50323746   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 5B, mitochondrial (Homo sapiens (Human))	BDBM50323746 (CHEMBL1214249 | N1,N3-bis(2-(2,2,2-trifluoroacetam...) Show SMILES FC(F)(F)C(=O)NCCNCCCNCCNC(=O)C(F)(F)F Show InChI InChI=1S/C11H18F6N4O2/c12-10(13,14)8(22)20-6-4-18-2-1-3-19-5-7-21-9(23)11(15,16)17/h18-19H,1-7H2,(H,20,22)(H,21,23)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	5.40E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 5B by stopped flow CO2 hydration method				J Med Chem 53: 5511-22 (2010) Article DOI: 10.1021/jm1003667 BindingDB Entry DOI: 10.7270/Q22N52FB
					More data for this Ligand-Target Pair
Carbonic anhydrase 5A, mitochondrial (Homo sapiens (Human))	BDBM50323746 (CHEMBL1214249 | N1,N3-bis(2-(2,2,2-trifluoroacetam...) Show SMILES FC(F)(F)C(=O)NCCNCCCNCCNC(=O)C(F)(F)F Show InChI InChI=1S/C11H18F6N4O2/c12-10(13,14)8(22)20-6-4-18-2-1-3-19-5-7-21-9(23)11(15,16)17/h18-19H,1-7H2,(H,20,22)(H,21,23)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	6.20E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 5A by stopped flow CO2 hydration method				J Med Chem 53: 5511-22 (2010) Article DOI: 10.1021/jm1003667 BindingDB Entry DOI: 10.7270/Q22N52FB
					More data for this Ligand-Target Pair
Carbonic anhydrase 3 (Homo sapiens (Human))	BDBM50323746 (CHEMBL1214249 | N1,N3-bis(2-(2,2,2-trifluoroacetam...) Show SMILES FC(F)(F)C(=O)NCCNCCCNCCNC(=O)C(F)(F)F Show InChI InChI=1S/C11H18F6N4O2/c12-10(13,14)8(22)20-6-4-18-2-1-3-19-5-7-21-9(23)11(15,16)17/h18-19H,1-7H2,(H,20,22)(H,21,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	9.60E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 3 by stopped flow CO2 hydration method				J Med Chem 53: 5511-22 (2010) Article DOI: 10.1021/jm1003667 BindingDB Entry DOI: 10.7270/Q22N52FB
					More data for this Ligand-Target Pair
Carbonic anhydrase 15 (Mus musculus)	BDBM50323746 (CHEMBL1214249 | N1,N3-bis(2-(2,2,2-trifluoroacetam...) Show SMILES FC(F)(F)C(=O)NCCNCCCNCCNC(=O)C(F)(F)F Show InChI InChI=1S/C11H18F6N4O2/c12-10(13,14)8(22)20-6-4-18-2-1-3-19-5-7-21-9(23)11(15,16)17/h18-19H,1-7H2,(H,20,22)(H,21,23)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.04E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibition of mouse carbonic anhydrase 15 by stopped flow CO2 hydration method				J Med Chem 53: 5511-22 (2010) Article DOI: 10.1021/jm1003667 BindingDB Entry DOI: 10.7270/Q22N52FB
					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Homo sapiens (Human))	BDBM50323746 (CHEMBL1214249 | N1,N3-bis(2-(2,2,2-trifluoroacetam...) Show SMILES FC(F)(F)C(=O)NCCNCCCNCCNC(=O)C(F)(F)F Show InChI InChI=1S/C11H18F6N4O2/c12-10(13,14)8(22)20-6-4-18-2-1-3-19-5-7-21-9(23)11(15,16)17/h18-19H,1-7H2,(H,20,22)(H,21,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.08E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 7 by stopped flow CO2 hydration method				J Med Chem 53: 5511-22 (2010) Article DOI: 10.1021/jm1003667 BindingDB Entry DOI: 10.7270/Q22N52FB
					More data for this Ligand-Target Pair
Carbonic anhydrase 4 (Homo sapiens (Human))	BDBM50323746 (CHEMBL1214249 | N1,N3-bis(2-(2,2,2-trifluoroacetam...) Show SMILES FC(F)(F)C(=O)NCCNCCCNCCNC(=O)C(F)(F)F Show InChI InChI=1S/C11H18F6N4O2/c12-10(13,14)8(22)20-6-4-18-2-1-3-19-5-7-21-9(23)11(15,16)17/h18-19H,1-7H2,(H,20,22)(H,21,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.08E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 4 by stopped flow CO2 hydration method				J Med Chem 53: 5511-22 (2010) Article DOI: 10.1021/jm1003667 BindingDB Entry DOI: 10.7270/Q22N52FB
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50323746 (CHEMBL1214249 | N1,N3-bis(2-(2,2,2-trifluoroacetam...) Show SMILES FC(F)(F)C(=O)NCCNCCCNCCNC(=O)C(F)(F)F Show InChI InChI=1S/C11H18F6N4O2/c12-10(13,14)8(22)20-6-4-18-2-1-3-19-5-7-21-9(23)11(15,16)17/h18-19H,1-7H2,(H,20,22)(H,21,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.12E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 2 by stopped flow CO2 hydration method				J Med Chem 53: 5511-22 (2010) Article DOI: 10.1021/jm1003667 BindingDB Entry DOI: 10.7270/Q22N52FB
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Homo sapiens (Human))	BDBM50323746 (CHEMBL1214249 | N1,N3-bis(2-(2,2,2-trifluoroacetam...) Show SMILES FC(F)(F)C(=O)NCCNCCCNCCNC(=O)C(F)(F)F Show InChI InChI=1S/C11H18F6N4O2/c12-10(13,14)8(22)20-6-4-18-2-1-3-19-5-7-21-9(23)11(15,16)17/h18-19H,1-7H2,(H,20,22)(H,21,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.12E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 12 by stopped flow CO2 hydration method				J Med Chem 53: 5511-22 (2010) Article DOI: 10.1021/jm1003667 BindingDB Entry DOI: 10.7270/Q22N52FB
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Homo sapiens (Human))	BDBM50323746 (CHEMBL1214249 | N1,N3-bis(2-(2,2,2-trifluoroacetam...) Show SMILES FC(F)(F)C(=O)NCCNCCCNCCNC(=O)C(F)(F)F Show InChI InChI=1S/C11H18F6N4O2/c12-10(13,14)8(22)20-6-4-18-2-1-3-19-5-7-21-9(23)11(15,16)17/h18-19H,1-7H2,(H,20,22)(H,21,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.17E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 9 by stopped flow CO2 hydration method				J Med Chem 53: 5511-22 (2010) Article DOI: 10.1021/jm1003667 BindingDB Entry DOI: 10.7270/Q22N52FB
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM50323746 (CHEMBL1214249 | N1,N3-bis(2-(2,2,2-trifluoroacetam...) Show SMILES FC(F)(F)C(=O)NCCNCCCNCCNC(=O)C(F)(F)F Show InChI InChI=1S/C11H18F6N4O2/c12-10(13,14)8(22)20-6-4-18-2-1-3-19-5-7-21-9(23)11(15,16)17/h18-19H,1-7H2,(H,20,22)(H,21,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.22E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 1 by stopped flow CO2 hydration method				J Med Chem 53: 5511-22 (2010) Article DOI: 10.1021/jm1003667 BindingDB Entry DOI: 10.7270/Q22N52FB
					More data for this Ligand-Target Pair
Carbonic anhydrase 14 (Homo sapiens (Human))	BDBM50323746 (CHEMBL1214249 | N1,N3-bis(2-(2,2,2-trifluoroacetam...) Show SMILES FC(F)(F)C(=O)NCCNCCCNCCNC(=O)C(F)(F)F Show InChI InChI=1S/C11H18F6N4O2/c12-10(13,14)8(22)20-6-4-18-2-1-3-19-5-7-21-9(23)11(15,16)17/h18-19H,1-7H2,(H,20,22)(H,21,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.25E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 14 by stopped flow CO2 hydration method				J Med Chem 53: 5511-22 (2010) Article DOI: 10.1021/jm1003667 BindingDB Entry DOI: 10.7270/Q22N52FB
					More data for this Ligand-Target Pair
Carbonic anhydrase 13 (Mus musculus (mouse))	BDBM50323746 (CHEMBL1214249 | N1,N3-bis(2-(2,2,2-trifluoroacetam...) Show SMILES FC(F)(F)C(=O)NCCNCCCNCCNC(=O)C(F)(F)F Show InChI InChI=1S/C11H18F6N4O2/c12-10(13,14)8(22)20-6-4-18-2-1-3-19-5-7-21-9(23)11(15,16)17/h18-19H,1-7H2,(H,20,22)(H,21,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.31E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibition of mouse carbonic anhydrase 13 by stopped flow CO2 hydration method				J Med Chem 53: 5511-22 (2010) Article DOI: 10.1021/jm1003667 BindingDB Entry DOI: 10.7270/Q22N52FB
					More data for this Ligand-Target Pair
Carbonic anhydrase 6 (Homo sapiens (Human))	BDBM50323746 (CHEMBL1214249 | N1,N3-bis(2-(2,2,2-trifluoroacetam...) Show SMILES FC(F)(F)C(=O)NCCNCCCNCCNC(=O)C(F)(F)F Show InChI InChI=1S/C11H18F6N4O2/c12-10(13,14)8(22)20-6-4-18-2-1-3-19-5-7-21-9(23)11(15,16)17/h18-19H,1-7H2,(H,20,22)(H,21,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.56E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 6 by stopped flow CO2 hydration method				J Med Chem 53: 5511-22 (2010) Article DOI: 10.1021/jm1003667 BindingDB Entry DOI: 10.7270/Q22N52FB
					More data for this Ligand-Target Pair