BDBM50324216 (+/-)-(3SR,3aRS)-2-(4-Cyano-3-methoxyphenyl)-3-cyclopentyl-3,3a,4,5-tetrahydro-2H-benzo[g]indazole-7-carboxylic Acid::CHEMBL1215487

SMILES: COc1cc(ccc1C#N)N1N=C2[C@H](CCc3cc(ccc23)C(O)=O)[C@@H]1C1CCCC1

InChI Key: InChIKey=DIXPGEVTBJXMRW-URXFXBBRSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50324216   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mineralocorticoid receptor (Homo sapiens (Human))	BDBM50324216 ((+/-)-(3SR,3aRS)-2-(4-Cyano-3-methoxyphenyl)-3-cyc...) Show SMILES COc1cc(ccc1C#N)N1N=C2[C@H](CCc3cc(ccc23)C(O)=O)[C@@H]1C1CCCC1 |r,c:12| Show InChI InChI=1S/C25H25N3O3/c1-31-22-13-19(9-6-18(22)14-26)28-24(15-4-2-3-5-15)21-11-7-16-12-17(25(29)30)8-10-20(16)23(21)27-28/h6,8-10,12-13,15,21,24H,2-5,7,11H2,1H3,(H,29,30)/t21-,24-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Antagonist activity at Gal4-tagged mineralocorticoid receptor expressed in human Huh7 cells by luciferase reporter gene assay				J Med Chem 53: 5979-6002 (2010) Article DOI: 10.1021/jm100505n BindingDB Entry DOI: 10.7270/Q2T43V2T
					More data for this Ligand-Target Pair