BDBM50324396 (E)-4-(6,8-Dichloro-2-(4-nitrostyryl)-4-oxoquinazolin-3(4H)-yl)-benzoic Acid::CHEMBL1215225

SMILES: OC(=O)c1ccc(cc1)-n1c(\C=C\c2ccc(cc2)[N+]([O-])=O)nc2c(Cl)cc(Cl)cc2c1=O

InChI Key: InChIKey=JFFQDELRJWFZIL-XCVCLJGOSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50324396   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor 1 (Rattus norvegicus (Rat))	BDBM50324396 ((E)-4-(6,8-Dichloro-2-(4-nitrostyryl)-4-oxoquinazo...) Show SMILES OC(=O)c1ccc(cc1)-n1c(\C=C\c2ccc(cc2)[N+]([O-])=O)nc2c(Cl)cc(Cl)cc2c1=O Show InChI InChI=1S/C23H13Cl2N3O5/c24-15-11-18-21(19(25)12-15)26-20(10-3-13-1-6-17(7-2-13)28(32)33)27(22(18)29)16-8-4-14(5-9-16)23(30)31/h1-12H,(H,30,31)/b10-3+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Antagonist activity at rat recombinant GLuR1 expressed in Xenopus oocytes assessed as inhibition of glutamate-induced current by two-electrode voltag...				J Med Chem 53: 5476-90 (2010) Article DOI: 10.1021/jm100027p BindingDB Entry DOI: 10.7270/Q2DR2VQF
					More data for this Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 1/zeta 1 (Rattus norvegicus (Rat)-RAT)	BDBM50324396 ((E)-4-(6,8-Dichloro-2-(4-nitrostyryl)-4-oxoquinazo...) Show SMILES OC(=O)c1ccc(cc1)-n1c(\C=C\c2ccc(cc2)[N+]([O-])=O)nc2c(Cl)cc(Cl)cc2c1=O Show InChI InChI=1S/C23H13Cl2N3O5/c24-15-11-18-21(19(25)12-15)26-20(10-3-13-1-6-17(7-2-13)28(32)33)27(22(18)29)16-8-4-14(5-9-16)23(30)31/h1-12H,(H,30,31)/b10-3+	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Antagonist activity at rat recombinant NR1-NR2A receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...				J Med Chem 53: 5476-90 (2010) Article DOI: 10.1021/jm100027p BindingDB Entry DOI: 10.7270/Q2DR2VQF
					More data for this Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 2/zeta 1 (Rattus norvegicus (Rat)-RAT)	BDBM50324396 ((E)-4-(6,8-Dichloro-2-(4-nitrostyryl)-4-oxoquinazo...) Show SMILES OC(=O)c1ccc(cc1)-n1c(\C=C\c2ccc(cc2)[N+]([O-])=O)nc2c(Cl)cc(Cl)cc2c1=O Show InChI InChI=1S/C23H13Cl2N3O5/c24-15-11-18-21(19(25)12-15)26-20(10-3-13-1-6-17(7-2-13)28(32)33)27(22(18)29)16-8-4-14(5-9-16)23(30)31/h1-12H,(H,30,31)/b10-3+	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Antagonist activity at rat recombinant NR1-NR2B receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...				J Med Chem 53: 5476-90 (2010) Article DOI: 10.1021/jm100027p BindingDB Entry DOI: 10.7270/Q2DR2VQF
					More data for this Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 3/zeta 1 (RAT-Rattus norvegicus (Rat))	BDBM50324396 ((E)-4-(6,8-Dichloro-2-(4-nitrostyryl)-4-oxoquinazo...) Show SMILES OC(=O)c1ccc(cc1)-n1c(\C=C\c2ccc(cc2)[N+]([O-])=O)nc2c(Cl)cc(Cl)cc2c1=O Show InChI InChI=1S/C23H13Cl2N3O5/c24-15-11-18-21(19(25)12-15)26-20(10-3-13-1-6-17(7-2-13)28(32)33)27(22(18)29)16-8-4-14(5-9-16)23(30)31/h1-12H,(H,30,31)/b10-3+	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Antagonist activity at rat recombinant NR1-NR2C receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...				J Med Chem 53: 5476-90 (2010) Article DOI: 10.1021/jm100027p BindingDB Entry DOI: 10.7270/Q2DR2VQF
					More data for this Ligand-Target Pair