BDBM50324410 (E)-4-(2-(3-nitrostyryl)-4-oxo-6-(thiophen-2-yl)quinazolin-3(4H)-yl)benzoic acid::CHEMBL1215442

SMILES: OC(=O)c1ccc(cc1)-n1c(\C=C\c2cccc(c2)[N+]([O-])=O)nc2ccc(cc2c1=O)-c1cccs1

InChI Key: InChIKey=BOXNUIJOBFSQPT-AWNIVKPZSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50324410   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor 1 (Rattus norvegicus (Rat))	BDBM50324410 ((E)-4-(2-(3-nitrostyryl)-4-oxo-6-(thiophen-2-yl)qu...) Show SMILES OC(=O)c1ccc(cc1)-n1c(\C=C\c2cccc(c2)[N+]([O-])=O)nc2ccc(cc2c1=O)-c1cccs1 Show InChI InChI=1S/C27H17N3O5S/c31-26-22-16-19(24-5-2-14-36-24)9-12-23(22)28-25(13-6-17-3-1-4-21(15-17)30(34)35)29(26)20-10-7-18(8-11-20)27(32)33/h1-16H,(H,32,33)/b13-6+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.80E+5	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Antagonist activity at rat recombinant GLuR1 expressed in Xenopus oocytes assessed as inhibition of glutamate-induced current by two-electrode voltag...				J Med Chem 53: 5476-90 (2010) Article DOI: 10.1021/jm100027p BindingDB Entry DOI: 10.7270/Q2DR2VQF
					More data for this Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 3/zeta 1 (RAT-Rattus norvegicus (Rat))	BDBM50324410 ((E)-4-(2-(3-nitrostyryl)-4-oxo-6-(thiophen-2-yl)qu...) Show SMILES OC(=O)c1ccc(cc1)-n1c(\C=C\c2cccc(c2)[N+]([O-])=O)nc2ccc(cc2c1=O)-c1cccs1 Show InChI InChI=1S/C27H17N3O5S/c31-26-22-16-19(24-5-2-14-36-24)9-12-23(22)28-25(13-6-17-3-1-4-21(15-17)30(34)35)29(26)20-10-7-18(8-11-20)27(32)33/h1-16H,(H,32,33)/b13-6+	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Antagonist activity at rat recombinant NR1-NR2C receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...				J Med Chem 53: 5476-90 (2010) Article DOI: 10.1021/jm100027p BindingDB Entry DOI: 10.7270/Q2DR2VQF
					More data for this Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 1/zeta 1 (Rattus norvegicus (Rat)-RAT)	BDBM50324410 ((E)-4-(2-(3-nitrostyryl)-4-oxo-6-(thiophen-2-yl)qu...) Show SMILES OC(=O)c1ccc(cc1)-n1c(\C=C\c2cccc(c2)[N+]([O-])=O)nc2ccc(cc2c1=O)-c1cccs1 Show InChI InChI=1S/C27H17N3O5S/c31-26-22-16-19(24-5-2-14-36-24)9-12-23(22)28-25(13-6-17-3-1-4-21(15-17)30(34)35)29(26)20-10-7-18(8-11-20)27(32)33/h1-16H,(H,32,33)/b13-6+	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.57E+5	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Antagonist activity at rat recombinant NR1-NR2A receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...				J Med Chem 53: 5476-90 (2010) Article DOI: 10.1021/jm100027p BindingDB Entry DOI: 10.7270/Q2DR2VQF
					More data for this Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 2/zeta 1 (Rattus norvegicus (Rat)-RAT)	BDBM50324410 ((E)-4-(2-(3-nitrostyryl)-4-oxo-6-(thiophen-2-yl)qu...) Show SMILES OC(=O)c1ccc(cc1)-n1c(\C=C\c2cccc(c2)[N+]([O-])=O)nc2ccc(cc2c1=O)-c1cccs1 Show InChI InChI=1S/C27H17N3O5S/c31-26-22-16-19(24-5-2-14-36-24)9-12-23(22)28-25(13-6-17-3-1-4-21(15-17)30(34)35)29(26)20-10-7-18(8-11-20)27(32)33/h1-16H,(H,32,33)/b13-6+	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.29E+5	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Antagonist activity at rat recombinant NR1-NR2B receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...				J Med Chem 53: 5476-90 (2010) Article DOI: 10.1021/jm100027p BindingDB Entry DOI: 10.7270/Q2DR2VQF
					More data for this Ligand-Target Pair