BDBM50324411 4-(2-(3-Nitrostyryl)-4-oxo-6-styrylquinazolin-3(4H)-yl)benzoicAcid::CHEMBL1215510

SMILES: OC(=O)c1ccc(cc1)-n1c(\C=C\c2cccc(c2)[N+]([O-])=O)nc2ccc(\C=C\c3ccccc3)cc2c1=O

InChI Key: InChIKey=YAFQLVVRTOWGQM-DBJUCQNNSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50324411   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor 1 (Rattus norvegicus (Rat))	BDBM50324411 (4-(2-(3-Nitrostyryl)-4-oxo-6-styrylquinazolin-3(4H...) Show SMILES OC(=O)c1ccc(cc1)-n1c(\C=C\c2cccc(c2)[N+]([O-])=O)nc2ccc(\C=C\c3ccccc3)cc2c1=O Show InChI InChI=1S/C31H21N3O5/c35-30-27-20-23(10-9-21-5-2-1-3-6-21)11-17-28(27)32-29(18-12-22-7-4-8-26(19-22)34(38)39)33(30)25-15-13-24(14-16-25)31(36)37/h1-20H,(H,36,37)/b10-9+,18-12+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.31E+5	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Antagonist activity at rat recombinant GLuR1 expressed in Xenopus oocytes assessed as inhibition of glutamate-induced current by two-electrode voltag...				J Med Chem 53: 5476-90 (2010) Article DOI: 10.1021/jm100027p BindingDB Entry DOI: 10.7270/Q2DR2VQF
					More data for this Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 3/zeta 1 (RAT-Rattus norvegicus (Rat))	BDBM50324411 (4-(2-(3-Nitrostyryl)-4-oxo-6-styrylquinazolin-3(4H...) Show SMILES OC(=O)c1ccc(cc1)-n1c(\C=C\c2cccc(c2)[N+]([O-])=O)nc2ccc(\C=C\c3ccccc3)cc2c1=O Show InChI InChI=1S/C31H21N3O5/c35-30-27-20-23(10-9-21-5-2-1-3-6-21)11-17-28(27)32-29(18-12-22-7-4-8-26(19-22)34(38)39)33(30)25-15-13-24(14-16-25)31(36)37/h1-20H,(H,36,37)/b10-9+,18-12+	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Antagonist activity at rat recombinant NR1-NR2C receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...				J Med Chem 53: 5476-90 (2010) Article DOI: 10.1021/jm100027p BindingDB Entry DOI: 10.7270/Q2DR2VQF
					More data for this Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 1/zeta 1 (Rattus norvegicus (Rat)-RAT)	BDBM50324411 (4-(2-(3-Nitrostyryl)-4-oxo-6-styrylquinazolin-3(4H...) Show SMILES OC(=O)c1ccc(cc1)-n1c(\C=C\c2cccc(c2)[N+]([O-])=O)nc2ccc(\C=C\c3ccccc3)cc2c1=O Show InChI InChI=1S/C31H21N3O5/c35-30-27-20-23(10-9-21-5-2-1-3-6-21)11-17-28(27)32-29(18-12-22-7-4-8-26(19-22)34(38)39)33(30)25-15-13-24(14-16-25)31(36)37/h1-20H,(H,36,37)/b10-9+,18-12+	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Antagonist activity at rat recombinant NR1-NR2A receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...				J Med Chem 53: 5476-90 (2010) Article DOI: 10.1021/jm100027p BindingDB Entry DOI: 10.7270/Q2DR2VQF
					More data for this Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 2/zeta 1 (Rattus norvegicus (Rat)-RAT)	BDBM50324411 (4-(2-(3-Nitrostyryl)-4-oxo-6-styrylquinazolin-3(4H...) Show SMILES OC(=O)c1ccc(cc1)-n1c(\C=C\c2cccc(c2)[N+]([O-])=O)nc2ccc(\C=C\c3ccccc3)cc2c1=O Show InChI InChI=1S/C31H21N3O5/c35-30-27-20-23(10-9-21-5-2-1-3-6-21)11-17-28(27)32-29(18-12-22-7-4-8-26(19-22)34(38)39)33(30)25-15-13-24(14-16-25)31(36)37/h1-20H,(H,36,37)/b10-9+,18-12+	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Antagonist activity at rat recombinant NR1-NR2B receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...				J Med Chem 53: 5476-90 (2010) Article DOI: 10.1021/jm100027p BindingDB Entry DOI: 10.7270/Q2DR2VQF
					More data for this Ligand-Target Pair