BDBM50324429 (E)-4-(6-Methoxy-2-(4-nitrostyryl)-4-oxoquinazolin-3(4H)-yl)-benzoic Acid::CHEMBL1215802

SMILES: COc1ccc2nc(\C=C\c3ccc(cc3)[N+]([O-])=O)n(-c3ccc(cc3)C(O)=O)c(=O)c2c1

InChI Key: InChIKey=ILZHIKMHEYERHC-YIXHJXPBSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50324429   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate [NMDA] receptor subunit epsilon 3/zeta 1 (RAT-Rattus norvegicus (Rat))	BDBM50324429 ((E)-4-(6-Methoxy-2-(4-nitrostyryl)-4-oxoquinazolin...) Show SMILES COc1ccc2nc(\C=C\c3ccc(cc3)[N+]([O-])=O)n(-c3ccc(cc3)C(O)=O)c(=O)c2c1 Show InChI InChI=1S/C24H17N3O6/c1-33-19-11-12-21-20(14-19)23(28)26(17-9-5-16(6-10-17)24(29)30)22(25-21)13-4-15-2-7-18(8-3-15)27(31)32/h2-14H,1H3,(H,29,30)/b13-4+	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Antagonist activity at rat recombinant NR1-NR2C receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...				J Med Chem 53: 5476-90 (2010) Article DOI: 10.1021/jm100027p BindingDB Entry DOI: 10.7270/Q2DR2VQF
					More data for this Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 1/zeta 1 (Rattus norvegicus (Rat)-RAT)	BDBM50324429 ((E)-4-(6-Methoxy-2-(4-nitrostyryl)-4-oxoquinazolin...) Show SMILES COc1ccc2nc(\C=C\c3ccc(cc3)[N+]([O-])=O)n(-c3ccc(cc3)C(O)=O)c(=O)c2c1 Show InChI InChI=1S/C24H17N3O6/c1-33-19-11-12-21-20(14-19)23(28)26(17-9-5-16(6-10-17)24(29)30)22(25-21)13-4-15-2-7-18(8-3-15)27(31)32/h2-14H,1H3,(H,29,30)/b13-4+	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.97E+5	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Antagonist activity at rat recombinant NR1-NR2A receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...				J Med Chem 53: 5476-90 (2010) Article DOI: 10.1021/jm100027p BindingDB Entry DOI: 10.7270/Q2DR2VQF
					More data for this Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 2/zeta 1 (Rattus norvegicus (Rat)-RAT)	BDBM50324429 ((E)-4-(6-Methoxy-2-(4-nitrostyryl)-4-oxoquinazolin...) Show SMILES COc1ccc2nc(\C=C\c3ccc(cc3)[N+]([O-])=O)n(-c3ccc(cc3)C(O)=O)c(=O)c2c1 Show InChI InChI=1S/C24H17N3O6/c1-33-19-11-12-21-20(14-19)23(28)26(17-9-5-16(6-10-17)24(29)30)22(25-21)13-4-15-2-7-18(8-3-15)27(31)32/h2-14H,1H3,(H,29,30)/b13-4+	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.06E+5	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Antagonist activity at rat recombinant NR1-NR2B receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...				J Med Chem 53: 5476-90 (2010) Article DOI: 10.1021/jm100027p BindingDB Entry DOI: 10.7270/Q2DR2VQF
					More data for this Ligand-Target Pair
Glutamate receptor 1 (Rattus norvegicus (Rat))	BDBM50324429 ((E)-4-(6-Methoxy-2-(4-nitrostyryl)-4-oxoquinazolin...) Show SMILES COc1ccc2nc(\C=C\c3ccc(cc3)[N+]([O-])=O)n(-c3ccc(cc3)C(O)=O)c(=O)c2c1 Show InChI InChI=1S/C24H17N3O6/c1-33-19-11-12-21-20(14-19)23(28)26(17-9-5-16(6-10-17)24(29)30)22(25-21)13-4-15-2-7-18(8-3-15)27(31)32/h2-14H,1H3,(H,29,30)/b13-4+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Antagonist activity at rat recombinant GLuR1 expressed in Xenopus oocytes assessed as inhibition of glutamate-induced current by two-electrode voltag...				J Med Chem 53: 5476-90 (2010) Article DOI: 10.1021/jm100027p BindingDB Entry DOI: 10.7270/Q2DR2VQF
					More data for this Ligand-Target Pair