BDBM50324750 (3R,4R)-N3-(4-chlorophenyl)-N4-(2-fluoro-4-(2-oxopyridin-1(2H)-yl)phenyl)-1-(2-hydroxyethyl)pyrrolidine-3,4-dicarboxamide::CHEMBL1221579

SMILES: OCCN1C[C@@H]([C@H](C1)C(=O)Nc1ccc(cc1F)-n1ccccc1=O)C(=O)Nc1ccc(Cl)cc1

InChI Key: InChIKey=PKDZWYCTNYITJK-PMACEKPBSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50324750   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50324750 ((3R,4R)-N3-(4-chlorophenyl)-N4-(2-fluoro-4-(2-oxop...) Show SMILES OCCN1C[C@@H]([C@H](C1)C(=O)Nc1ccc(cc1F)-n1ccccc1=O)C(=O)Nc1ccc(Cl)cc1 |r| Show InChI InChI=1S/C25H24ClFN4O4/c26-16-4-6-17(7-5-16)28-24(34)19-14-30(11-12-32)15-20(19)25(35)29-22-9-8-18(13-21(22)27)31-10-2-1-3-23(31)33/h1-10,13,19-20,32H,11-12,14-15H2,(H,28,34)(H,29,35)/t19-,20-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Binding affinity to factor 10a				Bioorg Med Chem Lett 20: 5313-9 (2010) Article DOI: 10.1016/j.bmcl.2010.06.126 BindingDB Entry DOI: 10.7270/Q2542NSG
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50324750 ((3R,4R)-N3-(4-chlorophenyl)-N4-(2-fluoro-4-(2-oxop...) Show SMILES OCCN1C[C@@H]([C@H](C1)C(=O)Nc1ccc(cc1F)-n1ccccc1=O)C(=O)Nc1ccc(Cl)cc1 |r| Show InChI InChI=1S/C25H24ClFN4O4/c26-16-4-6-17(7-5-16)28-24(34)19-14-30(11-12-32)15-20(19)25(35)29-22-9-8-18(13-21(22)27)31-10-2-1-3-23(31)33/h1-10,13,19-20,32H,11-12,14-15H2,(H,28,34)(H,29,35)/t19-,20-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Inhibition of thrombin				Bioorg Med Chem Lett 20: 5313-9 (2010) Article DOI: 10.1016/j.bmcl.2010.06.126 BindingDB Entry DOI: 10.7270/Q2542NSG
					More data for this Ligand-Target Pair