BDBM50324891 CHEMBL1221591::N-(5-(4-(2-methoxyphenyl)piperazin-1-yl)pentyl)-2-naphthamide

SMILES: COc1ccccc1N1CCN(CCCCCNC(=O)c2ccc3ccccc3c2)CC1

InChI Key: InChIKey=WUTIBZPSZGYSGD-UHFFFAOYSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50324891   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(3) dopamine receptor (Rattus norvegicus (Rat))	BDBM50324891 (CHEMBL1221591 | N-(5-(4-(2-methoxyphenyl)piperazin...) Show SMILES COc1ccccc1N1CCN(CCCCCNC(=O)c2ccc3ccccc3c2)CC1 Show InChI InChI=1S/C27H33N3O2/c1-32-26-12-6-5-11-25(26)30-19-17-29(18-20-30)16-8-2-7-15-28-27(31)24-14-13-22-9-3-4-10-23(22)21-24/h3-6,9-14,21H,2,7-8,15-20H2,1H3,(H,28,31)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.36	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Liège Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from rat dopamine D3 receptor after 60 mins				Bioorg Med Chem Lett 20: 5199-202 (2010) Article DOI: 10.1016/j.bmcl.2010.07.002 BindingDB Entry DOI: 10.7270/Q2445MPJ
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM50324891 (CHEMBL1221591 | N-(5-(4-(2-methoxyphenyl)piperazin...) Show SMILES COc1ccccc1N1CCN(CCCCCNC(=O)c2ccc3ccccc3c2)CC1 Show InChI InChI=1S/C27H33N3O2/c1-32-26-12-6-5-11-25(26)30-19-17-29(18-20-30)16-8-2-7-15-28-27(31)24-14-13-22-9-3-4-10-23(22)21-24/h3-6,9-14,21H,2,7-8,15-20H2,1H3,(H,28,31)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	11.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Liège Curated by ChEMBL					Assay Description Displacement of [3H]MK912 from human alpha2A receptor after 60 mins				Bioorg Med Chem Lett 20: 5199-202 (2010) Article DOI: 10.1016/j.bmcl.2010.07.002 BindingDB Entry DOI: 10.7270/Q2445MPJ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50324891 (CHEMBL1221591 | N-(5-(4-(2-methoxyphenyl)piperazin...) Show SMILES COc1ccccc1N1CCN(CCCCCNC(=O)c2ccc3ccccc3c2)CC1 Show InChI InChI=1S/C27H33N3O2/c1-32-26-12-6-5-11-25(26)30-19-17-29(18-20-30)16-8-2-7-15-28-27(31)24-14-13-22-9-3-4-10-23(22)21-24/h3-6,9-14,21H,2,7-8,15-20H2,1H3,(H,28,31)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	54	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Liège Curated by ChEMBL					Assay Description Displacement of [3H]8OH-DPAT from human 5HT1A receptor after 60 mins				Bioorg Med Chem Lett 20: 5199-202 (2010) Article DOI: 10.1016/j.bmcl.2010.07.002 BindingDB Entry DOI: 10.7270/Q2445MPJ
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50324891 (CHEMBL1221591 | N-(5-(4-(2-methoxyphenyl)piperazin...) Show SMILES COc1ccccc1N1CCN(CCCCCNC(=O)c2ccc3ccccc3c2)CC1 Show InChI InChI=1S/C27H33N3O2/c1-32-26-12-6-5-11-25(26)30-19-17-29(18-20-30)16-8-2-7-15-28-27(31)24-14-13-22-9-3-4-10-23(22)21-24/h3-6,9-14,21H,2,7-8,15-20H2,1H3,(H,28,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	254	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Liège Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human D2L receptor after 60 mins				Bioorg Med Chem Lett 20: 5199-202 (2010) Article DOI: 10.1016/j.bmcl.2010.07.002 BindingDB Entry DOI: 10.7270/Q2445MPJ
					More data for this Ligand-Target Pair