BDBM50324895 2-[N-Ethyl(5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-2-naphthyl)]-5-(2H-tetrazol-5-yl)pyridinamine::CHEMBL1221640

SMILES: CCN(c1ccc2c(c1)C(C)(C)CCC2(C)C)c1ccc(cn1)-c1nnn[nH]1

InChI Key: InChIKey=LAVVEKRPDLBLLX-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50324895   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Retinoic acid receptor RXR-alpha (Homo sapiens (Human))	BDBM50324895 (2-[N-Ethyl(5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-...) Show SMILES CCN(c1ccc2c(c1)C(C)(C)CCC2(C)C)c1ccc(cn1)-c1nnn[nH]1 Show InChI InChI=1S/C22H28N6/c1-6-28(19-10-7-15(14-23-19)20-24-26-27-25-20)16-8-9-17-18(13-16)22(4,5)12-11-21(17,2)3/h7-10,13-14H,6,11-12H2,1-5H3,(H,24,25,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	205	n/a	n/a	n/a	n/a
Okayama University Curated by ChEMBL					Assay Description Agonist activity at RXRalpha by luciferase reporter gene assay				Bioorg Med Chem Lett 20: 5139-42 (2010) Article DOI: 10.1016/j.bmcl.2010.07.012 BindingDB Entry DOI: 10.7270/Q20G3KB3
					More data for this Ligand-Target Pair