BDBM50325025 (R)-5-((6-fluoro-1-oxoisoindolin-2-yl)methyl)-5-(4-(2-oxopyrrolidin-1-yl)phenyl)imidazolidine-2,4-dione::CHEMBL1222655

SMILES: Fc1ccc2CN(C[C@]3(NC(=O)NC3=O)c3ccc(cc3)N3CCCC3=O)C(=O)c2c1

InChI Key: InChIKey=ZYKDRBDNKSNCHT-QFIPXVFZSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50325025   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Disintegrin and metalloproteinase domain-containing protein 17 (Homo sapiens (Human))	BDBM50325025 ((R)-5-((6-fluoro-1-oxoisoindolin-2-yl)methyl)-5-(4...) Show SMILES Fc1ccc2CN(C[C@]3(NC(=O)NC3=O)c3ccc(cc3)N3CCCC3=O)C(=O)c2c1 |r| Show InChI InChI=1S/C22H19FN4O4/c23-15-6-3-13-11-26(19(29)17(13)10-15)12-22(20(30)24-21(31)25-22)14-4-7-16(8-5-14)27-9-1-2-18(27)28/h3-8,10H,1-2,9,11-12H2,(H2,24,25,30,31)/t22-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of TACE assessed as inhibition of pro-TNFalpha peptide cleavage				Bioorg Med Chem Lett 20: 5286-9 (2010) Article DOI: 10.1016/j.bmcl.2010.06.134 BindingDB Entry DOI: 10.7270/Q26W9B8K
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