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BDBM50325453 1-(1-(1-(furan-3-ylmethyl)piperidine-4-carbonyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one::CHEMBL1223151

SMILES: O=C(C1CCN(Cc2ccoc2)CC1)N1CCC(CC1)n1c2ccccc2[nH]c1=O

InChI Key: InChIKey=GBTHPFFWGZQZFV-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50325453   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
HRH3


(GUINEA PIG)		BDBM50325453
PNG
(1-(1-(1-(furan-3-ylmethyl)piperidine-4-carbonyl)pi...)
Show SMILES O=C(C1CCN(Cc2ccoc2)CC1)N1CCC(CC1)n1c2ccccc2[nH]c1=O
Show InChI InChI=1S/C23H28N4O3/c28-22(18-5-10-25(11-6-18)15-17-9-14-30-16-17)26-12-7-19(8-13-26)27-21-4-2-1-3-20(21)24-23(27)29/h1-4,9,14,16,18-19H,5-8,10-13,15H2,(H,24,29)
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Article
PubMed
 204n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]Nalpha-methylhistamine from histamine H3 receptor in guinea pig brain

Bioorg Med Chem Lett 20: 5004-8 (2010)


Article DOI: 10.1016/j.bmcl.2010.07.052
BindingDB Entry DOI: 10.7270/Q2N016QS
More data for this
Ligand-Target Pair