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BDBM50325456 1-(1-(1-(2-(pyridin-4-yl)ethyl)piperidine-4-carbonyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one::CHEMBL1223074

SMILES: O=C(C1CCN(CCc2ccncc2)CC1)N1CCC(CC1)n1c2ccccc2[nH]c1=O

InChI Key: InChIKey=BJLDKCODBKPRQX-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50325456   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
HRH3


(GUINEA PIG)		BDBM50325456
PNG
(1-(1-(1-(2-(pyridin-4-yl)ethyl)piperidine-4-carbon...)
Show SMILES O=C(C1CCN(CCc2ccncc2)CC1)N1CCC(CC1)n1c2ccccc2[nH]c1=O
Show InChI InChI=1S/C25H31N5O2/c31-24(20-8-15-28(16-9-20)14-7-19-5-12-26-13-6-19)29-17-10-21(11-18-29)30-23-4-2-1-3-22(23)27-25(30)32/h1-6,12-13,20-21H,7-11,14-18H2,(H,27,32)
UniProtKB/SwissProt

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Similars
Article
PubMed
 537n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]Nalpha-methylhistamine from histamine H3 receptor in guinea pig brain

Bioorg Med Chem Lett 20: 5004-8 (2010)


Article DOI: 10.1016/j.bmcl.2010.07.052
BindingDB Entry DOI: 10.7270/Q2N016QS
More data for this
Ligand-Target Pair