BDBM50325457 1-(1-(1-((3-chloropyridin-4-yl)methyl)piperidine-4-carbonyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one::CHEMBL1223073

SMILES: Clc1cnccc1CN1CCC(CC1)C(=O)N1CCC(CC1)n1c2ccccc2[nH]c1=O

InChI Key: InChIKey=IRHFYMJXRQFZOO-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50325457   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
HRH3 (GUINEA PIG)	BDBM50325457 (1-(1-(1-((3-chloropyridin-4-yl)methyl)piperidine-4...) Show SMILES Clc1cnccc1CN1CCC(CC1)C(=O)N1CCC(CC1)n1c2ccccc2[nH]c1=O Show InChI InChI=1S/C24H28ClN5O2/c25-20-15-26-10-5-18(20)16-28-11-6-17(7-12-28)23(31)29-13-8-19(9-14-29)30-22-4-2-1-3-21(22)27-24(30)32/h1-5,10,15,17,19H,6-9,11-14,16H2,(H,27,32)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	222	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]Nalpha-methylhistamine from histamine H3 receptor in guinea pig brain				Bioorg Med Chem Lett 20: 5004-8 (2010) Article DOI: 10.1016/j.bmcl.2010.07.052 BindingDB Entry DOI: 10.7270/Q2N016QS
					More data for this Ligand-Target Pair