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BDBM50325458 4-((4-(4-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidine-1-carbonyl)piperidin-1-yl)methyl)pyridine 1-oxide::CHEMBL1223072

SMILES: ON1C=CC(CN2CCC(CC2)C(=O)N2CCC(CC2)n2c3ccccc3[nH]c2=O)C=C1

InChI Key: InChIKey=LBOHAHKKUIYOKB-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50325458   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
HRH3


(GUINEA PIG)		BDBM50325458
PNG
(4-((4-(4-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-...)
Show SMILES ON1C=CC(CN2CCC(CC2)C(=O)N2CCC(CC2)n2c3ccccc3[nH]c2=O)C=C1 |c:2,34|
Show InChI InChI=1S/C24H31N5O3/c30-23(19-7-11-26(12-8-19)17-18-5-15-28(32)16-6-18)27-13-9-20(10-14-27)29-22-4-2-1-3-21(22)25-24(29)31/h1-6,15-16,18-20,32H,7-14,17H2,(H,25,31)
UniProtKB/SwissProt

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PC sid
UniChem

Similars
Article
PubMed
 440n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]Nalpha-methylhistamine from histamine H3 receptor in guinea pig brain

Bioorg Med Chem Lett 20: 5004-8 (2010)


Article DOI: 10.1016/j.bmcl.2010.07.052
BindingDB Entry DOI: 10.7270/Q2N016QS
More data for this
Ligand-Target Pair