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BDBM50325485 (4-benzylpiperazin-1-yl)(1-(pyridin-4-ylmethyl)piperidin-4-yl)methanone::CHEMBL1223503

SMILES: O=C(C1CCN(Cc2ccncc2)CC1)N1CCN(Cc2ccccc2)CC1

InChI Key: InChIKey=NQCVALFRSYNOCL-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50325485   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
HRH3


(GUINEA PIG)		BDBM50325485
PNG
((4-benzylpiperazin-1-yl)(1-(pyridin-4-ylmethyl)pip...)
Show SMILES O=C(C1CCN(Cc2ccncc2)CC1)N1CCN(Cc2ccccc2)CC1
Show InChI InChI=1S/C23H30N4O/c28-23(22-8-12-25(13-9-22)19-21-6-10-24-11-7-21)27-16-14-26(15-17-27)18-20-4-2-1-3-5-20/h1-7,10-11,22H,8-9,12-19H2
UniProtKB/SwissProt

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Article
PubMed
 28n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]Nalpha-methylhistamine from histamine H3 receptor in guinea pig brain

Bioorg Med Chem Lett 20: 5004-8 (2010)


Article DOI: 10.1016/j.bmcl.2010.07.052
BindingDB Entry DOI: 10.7270/Q2N016QS
More data for this
Ligand-Target Pair