BDBM50325772 5-tert-butyl-1-(2'-(trifluoromethoxy)biphenyl-3-yl)-1H-pyrazole-3-carboxamide::CHEMBL1221440

SMILES: CC(C)(C)c1cc(nn1-c1cccc(c1)-c1ccccc1OC(F)(F)F)C(N)=O

InChI Key: InChIKey=LWSIHALWURMCCX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50325772   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM50325772 (5-tert-butyl-1-(2'-(trifluoromethoxy)biphenyl-3-yl...) Show SMILES CC(C)(C)c1cc(nn1-c1cccc(c1)-c1ccccc1OC(F)(F)F)C(N)=O Show InChI InChI=1S/C21H20F3N3O2/c1-20(2,3)18-12-16(19(25)28)26-27(18)14-8-6-7-13(11-14)15-9-4-5-10-17(15)29-21(22,23)24/h4-12H,1-3H3,(H2,25,28)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.37E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human Nav 1.7 channel by voltage-ion-probe-reader				Bioorg Med Chem Lett 20: 5480-3 (2010) Article DOI: 10.1016/j.bmcl.2010.07.080 BindingDB Entry DOI: 10.7270/Q2PV6KJX
					More data for this Ligand-Target Pair