BDBM50325780 5-methyl-1-(2'-(2,2,2-trifluoroethoxy)biphenyl-3-yl)-1H-pyrazole-3-carboxamide::CHEMBL1224196

SMILES: Cc1cc(nn1-c1cccc(c1)-c1ccccc1OCC(F)(F)F)C(N)=O

InChI Key: InChIKey=QIWURTIQNCWINM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50325780   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM50325780 (5-methyl-1-(2'-(2,2,2-trifluoroethoxy)biphenyl-3-y...) Show SMILES Cc1cc(nn1-c1cccc(c1)-c1ccccc1OCC(F)(F)F)C(N)=O Show InChI InChI=1S/C19H16F3N3O2/c1-12-9-16(18(23)26)24-25(12)14-6-4-5-13(10-14)15-7-2-3-8-17(15)27-11-19(20,21)22/h2-10H,11H2,1H3,(H2,23,26)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	187	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human Nav 1.7 channel by voltage-ion-probe-reader				Bioorg Med Chem Lett 20: 5480-3 (2010) Article DOI: 10.1016/j.bmcl.2010.07.080 BindingDB Entry DOI: 10.7270/Q2PV6KJX
					More data for this Ligand-Target Pair