BDBM50325782 1-(6-fluoro-2'-(trifluoromethoxy)biphenyl-3-yl)-5-methyl-1H-pyrazole-3-carboxamide::CHEMBL1224431
SMILES: Cc1cc(nn1-c1ccc(F)c(c1)-c1ccccc1OC(F)(F)F)C(N)=O
InChI Key: InChIKey=AWSUASBKQXBDMZ-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Sodium channel protein type 9 subunit alpha (Homo sapiens (Human)) | BDBM50325782![]() (1-(6-fluoro-2'-(trifluoromethoxy)biphenyl-3-yl)-5-...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 162 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Inhibition of human Nav 1.7 channel by voltage-ion-probe-reader | Bioorg Med Chem Lett 20: 5480-3 (2010) Article DOI: 10.1016/j.bmcl.2010.07.080 BindingDB Entry DOI: 10.7270/Q2PV6KJX | |||||||||||
More data for this Ligand-Target Pair |