BDBM50325819 (Z)-5-((2'-(trifluoromethoxy)biphenyl-3-yl)methylene)thiazolidine-2,4-dione::CHEMBL1224435
SMILES: OC1=NC(=O)C(S1)=Cc1cccc(c1)-c1ccccc1OC(F)(F)F
InChI Key: InChIKey=SUCVKZFQEWRCCF-UHFFFAOYSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Sodium channel protein type 9 subunit alpha (Homo sapiens (Human)) | BDBM50325819![]() ((Z)-5-((2'-(trifluoromethoxy)biphenyl-3-yl)methyle...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Binding affinity to human Nav1.7 | Bioorg Med Chem Lett 20: 5536-40 (2010) Article DOI: 10.1016/j.bmcl.2010.07.064 BindingDB Entry DOI: 10.7270/Q2FB535G | |||||||||||
More data for this Ligand-Target Pair |