null
SMILES: NS(=O)(=O)c1cn(ccc1=O)-c1ncnc2nc[nH]c12
InChI Key: InChIKey=IQLVJIAYLAHSSP-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Carbonic anhydrase 9 (Homo sapiens (Human)) | BDBM50326111![]() (1,4-Dihydro-4-oxo-1-(6-purinyl)-3-pyridinesulfonam...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article PubMed | 68 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Medical University of Gdansk Curated by ChEMBL | Assay Description Inhibition of human cloned catalytic domain of CA9 after 15 mins by stopped-flow CO2 hydration assay | Eur J Med Chem 45: 3656-61 (2010) Article DOI: 10.1016/j.ejmech.2010.05.011 BindingDB Entry DOI: 10.7270/Q2SF2WCP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM50326111![]() (1,4-Dihydro-4-oxo-1-(6-purinyl)-3-pyridinesulfonam...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article PubMed | 95 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Medical University of Gdansk Curated by ChEMBL | Assay Description Inhibition of human cloned CA2 after 15 mins by stopped-flow CO2 hydration assay | Eur J Med Chem 45: 3656-61 (2010) Article DOI: 10.1016/j.ejmech.2010.05.011 BindingDB Entry DOI: 10.7270/Q2SF2WCP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 12 (Homo sapiens (Human)) | BDBM50326111![]() (1,4-Dihydro-4-oxo-1-(6-purinyl)-3-pyridinesulfonam...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article PubMed | 113 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Medical University of Gdansk Curated by ChEMBL | Assay Description Inhibition of human cloned catalytic domain of CA12 after 15 mins by stopped-flow CO2 hydration assay | Eur J Med Chem 45: 3656-61 (2010) Article DOI: 10.1016/j.ejmech.2010.05.011 BindingDB Entry DOI: 10.7270/Q2SF2WCP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 1 (Homo sapiens (Human)) | BDBM50326111![]() (1,4-Dihydro-4-oxo-1-(6-purinyl)-3-pyridinesulfonam...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article PubMed | 1.83E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Medical University of Gdansk Curated by ChEMBL | Assay Description Inhibition of human cloned CA1 after 15 mins by stopped-flow CO2 hydration assay | Eur J Med Chem 45: 3656-61 (2010) Article DOI: 10.1016/j.ejmech.2010.05.011 BindingDB Entry DOI: 10.7270/Q2SF2WCP | |||||||||||
More data for this Ligand-Target Pair |